When food is consumed uncooked, fewer digestive enzymes are required to perform the digestive function colitis-crohns The body will adapt to the plentiful, external supply by secreting fewer of its own enzymes, preserving them to assist in vital cellular metabolic functions colitis-crohns One of the worst cooking methods is frying, since since frying results in much higher temperatures than boiling colitis-crohns Frying damages protein as well as destroying enzymes colitis-crohns Enzymes can also be wasted by lifestyle factors colitis-crohns Enzymes work harder with increasing temperatures and are used up faster colitis-crohns A fever, for example, induces faster enzyme action and is therefore therefore unfavorable for bacterial activity colitis-crohns Enzymes can be found in urine after a fever, and also may be found after strenuous athletic activity colitis-crohns A natural behavior of animals is to harness the power of enzymes in food by burying or covering their food, allowing enzyme activity to start predigesting predigesting the food colitis-crohns By this natural behavior, animals instinctively preserve their own enzyme supply colitis-crohns Similarly, people of some native cultures also preserve their enzyme supply and disease prevention through efficient use of enzymes colitis-crohns Whales have up to 6 inches of fat to keep them warm, but their arteries arteries are not clogged colitis-crohns Eskimos, who frequently consume large quantities of fat, are often not obese colitis-crohns Both of these groups eat the fat-digesting enzyme lipase in the form of raw foods colitis-crohns Studies (both in vitro and controlled in vivo) using internal and parenteral routes have examined the effectiveness effectiveness of may different types and sources of plant enzymes in a several conditions, including poor digestion, poor absorption, pancreatic insufficiency, steatorrhea, lactose intolerance, celiac disease, obstruction of arteries, and thrombotic disease colitis-crohns Enzymes from the Aspergillus oryzae fungus were subjected to numerous studies evaluating their role in supporting healthy digestion colitis-crohns digestion colitis-crohns Additionally, human studies suggest the proteolytic enzymes derived from Aspergilus oryzae fungus may play a role in anti-inflammatory and fibrinolytic therapies colitis-crohns The enzymes appear to be relatively heat stable, and they are also active throughout a wide pH range colitis-crohns This is important because most enzymes are deactivated deactivated in stomach acid colitis-crohns These enzymes are synthesized from fungus, but contain no fungal residue even though that is their derivation colitis-crohns Modern filtration techniques and technology enable these fungal enzymes to be well suited for human consumption colitis-crohns According to Dr colitis-crohns Mark Percival (1985) , oral supplementation of of digestive enzymes taken just before or at mealtime can assist digestion colitis-crohns Even though most supplemental enzymes are labile and will deactivate when exposed to stomach acid, Dr colitis-crohns Percival believes some of the enzymes will remain active if they are taken with a meal or just before colitis-crohns Percival Percival says, The enzymes are physically protected by the meal and allow some enzymatic activity to occur in the stomach colitis-crohns The enzymes that get through to the small intestine may help with digestion there as well colitis-crohns pH plays a major role in enzymatic activity, therefore, the enzymes derived from from Aspergillus may be highly useful as they appear to be remarkably stable, even when subjected to an acidic environment colitis-crohns Additionally, Dr colitis-crohns Edward Howell (1986) adds that he chews an enzyme capsule with his food in order to start the digestive process as soon as the food is consumed | 