Rheumatic Disease that he had obtained good results with enzyme treatment of more than 700 patients with rheumatoid arthritis, osteoarthritis, or fibrositis: Some intractable cases of ankylosing spondylitis and Still's disease have also responded to this therapy indigestion-indigestion-gas He said that of 556 people with various types of arthritis, 283 were were much improved and 219 were improved to a less marked extent; of 292 people who had rheumatoid arthritis, 264 of them showed several degrees of improvement indigestion-indigestion-gas More time was required before improvement was seen when the duration of the disease had been long term, although most people started to to show some improvement after only 2 or 3 months of enzyme therapy indigestion-indigestion-gas In spite of these favorable findings, digestive enzyme therapy has been reserved for diseases that directly result in a pathological deficiency of pancreas-derived digestive enzymes indigestion-indigestion-gas According to Schneider et al indigestion-indigestion-gas (1985) , common digestive disorders disorders may benefit from enzyme replacement indigestion-indigestion-gas Oral intake of exocrine pancreatic enzymes is of key importance in the treatment of maldigestion in chronic pancreatitis with pancreatic insufficiency indigestion-indigestion-gas Schneider et al indigestion-indigestion-gas (1985) studied the therapeutic effectiveness of a conventional and an acid-protected enzyme preparation and an acid-stable fungal enzyme enzyme preparation in the treatment of severe pancreatogenic steatorrhea indigestion-indigestion-gas The results showed that a supplemental enzyme preparation is best for patients with chronic pancreatitis and those who underwent Whipple's procedure (a surgical procedure performed on pancreatic cancer patients) , while patients with an intact upper GIT do best with an an acid-protected porcine pancreatic enzyme preparation indigestion-indigestion-gas Rachman (1997) reported that 58% of the population has some type of digestive disorder and that lack of optimal digestive function associated with enzyme inadequacy may lead to malabsorption and other related conditions indigestion-indigestion-gas In the elderly, the problem is often exacerbated because the the elderly may have suboptimal production of gastric hydrocholoric acid indigestion-indigestion-gas This can be a significant factor that can impact nutrient absorption along with the creation of maldigestive-type symptoms indigestion-indigestion-gas Bacterial production of hydrogen and methane are determined after a carbohydrate challenge indigestion-indigestion-gas Excessive levels of these gases reflect overgrowth of of bacteria in the upper gut indigestion-indigestion-gas Rachman suggests there may be improvement with enzyme replacement indigestion-indigestion-gas He also adds that enzymes taken orally at meals may improve the digestion of dietary protein, thereby decreasing the quantity of antigenic macromolecules that leak across the intestinal wall into the bloodstream indigestion-indigestion-gas Such | 